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KMID : 0360220160570040582
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Journal of the Korean Ophthalmological Society
2016 Volume.57 No. 4 p.582 ~ p.587
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Influence of Intravitreal Bevacizumab Injection on Formation of Collateral Vessels in Branch Retinal Vein Occlusion
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손영우:Son Yeong Woo
이승우:Lee Seung-Woo
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Abstract
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Purpose: To evaluate the influence of retinal collateral vessels in eyes with macular edema secondary to branch retinal vein occlusion (BRVO) treated with intravitreal bevacizumab (IVB).
Methods: We reviewed the medical records of patients with BRVO who were followed up for 12 months. To compare formations of collateral vessels, the patients were divided into 2 groups. The treatment group included 20 patients (20 eyes) treated with IVB, and the control group included 41 patients (41 eyes) without treatment.
Results: In the treatment group, the mean age was 58.4 ± 9.5 years. The average number of IVB injections performed during the 12 months was 4.5 ± 2.5 (range 2 to 8). After 12 months from diagnosis, 13 eyes (65%) presented with collateral vessels. In the control group, the mean age was 60.6 ± 9.3 years and 28 eyes (68.3%) presented with collateral vessel after 12 months. There was no difference in incidence of collateral vessel formation between the treatment group and the control group (p = 0.574).
Conclusions: IVB does not influence the formation of retinal collateralization in eyes treated for macular edema secondary to BRVO.
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KEYWORD
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Bevacizumab, Collateral Vessels, Macular Edema, Retinal Vein Occlusion
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